|Application ||WB, IHC-P, E|
|Calculated MW||16393 Da|
|Other Names||Cystin-1, Cilia-associated protein, CYS1|
|Target/Specificity||This CYS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 142-177 amino acids from the C-terminal region of human CYS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CYS1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell projection, cilium membrane; Lipid-anchor. Cytoplasm, cytoskeleton, cilium axoneme. Note=Expression is enriched in the ciliary axoneme. Localization to cilium is mediated via interaction with UNC119 and UNC119B, which bind to the myristoyl moiety of the N-terminus|
|Tissue Location||Expressed at high levels in the kidney and pancreas. Moderate expression seen in the skeletal muscle, liver and heart. A weak expression seen in the brain, lung, uterus, prostate, testis, small intestine and colon|
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Provided below are standard protocols that you may find useful for product applications.
Fliegauf M.,et al.Pediatr. Nephrol. 18:498-505(2003).
Hou X.,et al.J. Clin. Invest. 109:533-540(2002).
Wright K.J.,et al.Genes Dev. 25:2347-2360(2011).
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