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PNP Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - PNP Antibody (Center) AP20740c
    Western blot analysis of lysates from Daudi, HT-1080, K562, MCF-7, MDA-MB-231 cell line (from left to right), using PNP Antibody (Center)(Cat. #AP20740c). AP20740c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysates at 35ug per lane.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00491
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 32118 Da
Additional Information
Gene ID 4860
Other Names Purine nucleoside phosphorylase, PNP, Inosine phosphorylase, Inosine-guanosine phosphorylase, PNP, NP
Target/Specificity This PNP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 145-178 amino acids from the Central region of human PNP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPNP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PNP
Synonyms NP
Function The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm
Tissue Location Expressed in red blood cells; overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology
Research Areas
Citations (0)

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The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.


Williams S.R.,et al.Nucleic Acids Res. 12:5779-5787(1984).
Williams S.R.,et al.J. Biol. Chem. 262:2332-2338(1987).
Yu L.,et al.Environ. Health Perspect. 111:1421-1427(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AP20740c
(40 western blots)
Availability: In Stock
Bulk Size
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