|Application ||WB, E|
|Calculated MW||63747 Da|
|Other Names||Tumor necrosis factor receptor superfamily member 8, CD30L receptor, Ki-1 antigen, Lymphocyte activation antigen CD30, CD30, TNFRSF8, CD30, D1S166E|
|Target/Specificity||This TNFRSF8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 30-63 amino acids from the N-terminal region of human TNFRSF8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TNFRSF8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B.
Duerkop H.,et al.Cell 68:421-427(1992).
Jung W.,et al.Mol. Immunol. 31:1329-1334(1994).
Horie R.,et al.Blood 88:2422-2432(1996).
Durkop H.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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