CYB5R2 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q6BCY4 |
Other Accession | Q6AY12, Q3KNK3 |
Reactivity | Human, Mouse |
Predicted | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 31458 Da |
Gene ID | 51700 |
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Other Names | NADH-cytochrome b5 reductase 2, b5R2, CYB5R2 |
Target/Specificity | This CYB5R2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 33-67 amino acids from the N-terminal region of human CYB5R2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CYB5R2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CYB5R2 (HGNC:24376) |
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Function | NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4- nitrophenyl]-5-[2,4-disulfophenyl]-2H tetrazolium monosodium salt (WST- 1). |
Tissue Location | Restricted expression. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NADH-cytochrome b5 reductases are involved in desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction (By similarity). Responsible for NADH-dependent lucigenin chemiluminescence in spermatozoa by reducing both lucigenin and 2-[4-iodophenyl]-3-[4-nitrophenyl]-5-[2,4- disulfophenyl]-2H tetrazolium monosodium salt (WST-1).
References
Zhu H.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:14742-14747(1999).
Baker M.A.,et al.Biol. Reprod. 73:334-342(2005).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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