|Application ||WB, E|
|Calculated MW||139315 Da|
|Other Names||ATP-dependent RNA helicase DHX8, DEAH box protein 8, RNA helicase HRH1, DHX8, DDX8|
|Target/Specificity||This DHX8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 339-373 amino acids from the N-terminal region of human DHX8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DHX8 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.|
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Provided below are standard protocols that you may find useful for product applications.
Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome.
Ono Y.,et al.Mol. Cell. Biol. 14:7611-7620(1994).
Ohno M.,et al.Genes Dev. 10:997-1007(1996).
Jurica M.S.,et al.RNA 8:426-439(2002).
Neuhaus E.M.,et al.J. Cell Sci. 119:3047-3056(2006).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
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