MRGPRX3 Antibody (N-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q96LB0 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36483 Da |
Gene ID | 117195 |
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Other Names | Mas-related G-protein coupled receptor member X3, Sensory neuron-specific G-protein coupled receptor 1/2, MRGPRX3, MRGX3, SNSR1, SNSR2 |
Target/Specificity | This MRGPRX3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 9-43 amino acids from the N-terminal region of human MRGPRX3. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MRGPRX3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MRGPRX3 |
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Synonyms | MRGX3, SNSR1, SNSR2 |
Function | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Location | Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins (By similarity).
References
Dong X.,et al.Cell 106:619-632(2001).
Lembo P.M.C.,et al.Nat. Neurosci. 5:201-209(2002).
Martin A.L.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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