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Mouse Kdm6b Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - Mouse Kdm6b Antibody (Center) AP20854c
    Western blot analysis of lysates from Hela cell line, mouse cerebellum tissue (from left to right), using Mouse Kdm6b Antibody (Center)(Cat. #AP20854c). AP20854c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q5NCY0
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 176355 Da
Additional Information
Gene ID 216850
Other Names Lysine-specific demethylase 6B, 11411-, JmjC domain-containing protein 3, Jumonji domain-containing protein 3, Kdm6b, Jmjd3, Kiaa0346
Target/Specificity This Mouse Kdm6b antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1023-1057 amino acids of Mouse Kdm6b.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Kdm6b Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Kdm6b
Synonyms Jmjd3, Kiaa0346
Function Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

References

Church D.M.,et al.PLoS Biol. 7:E1000112-E1000112(2009).
Okazaki N.,et al.DNA Res. 10:167-180(2003).
Carninci P.,et al.Science 309:1559-1563(2005).
De Santa F.,et al.Cell 130:1083-1094(2007).

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$ 295.00
$ 99.00
Cat# AP20854c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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