|Application ||WB, E|
|Calculated MW||59307 Da|
|Other Names||Transcription factor GATA-6, GATA-binding factor 6, Gata6|
|Target/Specificity||This Mouse Gata6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 544-577 amino acids from the C-terminal region of Mouse Gata6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Gata6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator that regulates SEMA3C and PLXNA2 (PubMed:19666519). May regulate genes that protect epithelial cells from bacterial infection (By similarity). Involved in gene regulation specifically in the gastric epithelium (By similarity). Involved in bone morphogenetic protein (BMP)- mediated cardiac-specific gene expression (PubMed:15329343). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (PubMed:15329343).|
|Tissue Location||Expressed in myocardium, vascular smooth muscle, gut epithelium, and osteoclasts|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional activator that regulates SEMA3C and PLXNA2. Involved in gene regulation specifically in the gastric epithelium (By similarity).
Morrisey E.E.,et al.Dev. Biol. 177:309-322(1996).
Katsuoka F.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Carninci P.,et al.Science 309:1559-1563(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Narita N.,et al.Genomics 36:345-348(1996).
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