|Application ||WB, E|
|Calculated MW||30621 Da|
|Other Names||Three prime repair exonuclease 2, 3'-5' exonuclease TREX2, TREX2|
|Target/Specificity||This TREX2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 264-299 amino acids from the C-terminal region of human TREX2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TREX2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.|
|Tissue Location||Detected in heart, breast, prostate, skeletal muscle, testis, uterus, bone marrow, colon, small intestine, stomach and thymus.|
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Provided below are standard protocols that you may find useful for product applications.
Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
Mazur D.J.,et al.J. Biol. Chem. 274:19655-19660(1999).
Mazur D.J.,et al.J. Biol. Chem. 276:14718-14727(2001).
Mazur D.J.,et al.J. Biol. Chem. 276:17022-17029(2001).
Perrino F.W.,et al.J. Biol. Chem. 280:15212-15218(2005).
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