|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||284539 Da|
|Other Names||Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit, SPTAN1, NEAS, SPTA2|
|Target/Specificity||This SPTAN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 977-991 amino acids from the Central region of human SPTAN1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SPTAN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Moon R.T.,et al.J. Biol. Chem. 265:4427-4433(1990).
Cianci C.D.,et al.Biochemistry 38:15721-15730(1999).
Kato S.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
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