|Application ||WB, IHC, FC, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||42731 Da|
|Other Names||Neuropeptide Y receptor type 2, NPY2-R, NPY-Y2 receptor, Y2 receptor, NPY2R|
|Target/Specificity||This NPY2R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 29-65 amino acids from the N-terminal region of human NPY2R.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NPY2R Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||High levels in amygdala, corpus callosum, hippocampus and subthalamic nucleus. Also detectable in caudate nucleus, hypothalamus and substantia nigra|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Gerald C.,et al.J. Biol. Chem. 270:26758-26761(1995).
Gehlert D.R.,et al.Mol. Pharmacol. 49:224-228(1996).
Rose P.M.,et al.J. Biol. Chem. 270:22661-22664(1995).
Yan H.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996).
Ammar D.A.,et al.Genomics 38:392-398(1996).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.