BZRAP1 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O95153 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 200051 Da |
Antigen Region | 1551-1585 aa |
Gene ID | 9256 |
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Other Names | Peripheral-type benzodiazepine receptor-associated protein 1, PRAX-1, Peripheral benzodiazepine receptor-interacting protein, PBR-IP, RIMS-binding protein 1, RIM-BP1, BZRAP1, KIAA0612, RBP1, RIMBP1 |
Target/Specificity | This BZRAP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1551-1585 amino acids from the C-terminal region of human BZRAP1. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | BZRAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSPOAP1 (HGNC:16831) |
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Function | Required for synaptic transmission regulation (PubMed:33539324). It probably controls the recruitement of voltage- gated calcium channels to the presynaptic membrane, and modulates neurotransmitter release. |
Cellular Location | Cytoplasm. Mitochondrion. Note=Preferentially expressed in the mitochondria in the presence of TSPO |
Tissue Location | Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus |
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Provided below are standard protocols that you may find useful for product applications.
References
Galiegue S.,et al.J. Biol. Chem. 274:2938-2952(1999).
Ishikawa K.,et al.DNA Res. 5:169-176(1998).
Parry D.A.,et al.Am. J. Hum. Genet. 92:307-312(2013).
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