|Application ||WB, E|
|Calculated MW||75712 Da|
|Other Names||CXXC-type zinc finger protein 1, CpG-binding protein, PHD finger and CXXC domain-containing protein 1, CXXC1, CFP1, CGBP, PCCX1, PHF18|
|Target/Specificity||This CXXC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 355-389 amino acids from the C-terminal region of human CXXC1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CXXC1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CFP1, CGBP, PCCX1, PHF18|
|Function||Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.|
|Cellular Location||Nucleus speckle Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Voo K.S.,et al.Mol. Cell. Biol. 20:2108-2121(2000).
Fujino T.,et al.Biochem. Biophys. Res. Commun. 271:305-310(2000).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nusbaum C.,et al.Nature 437:551-555(2005).
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