|Application ||WB, E|
|Calculated MW||41173 Da|
|Other Names||C-C chemokine receptor type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, MIP-1alpha-R, RANTES-R, CD191, CCR1, CMKBR1, CMKR1, SCYAR1|
|Target/Specificity||This CCR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 13-44 amino acids from the N-terminal region of human CCR1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CMKBR1, CMKR1, SCYAR1|
|Function||Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Widely expressed in different hematopoietic cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-delta, RANTES, and MCP-3 and, less efficiently, to MIP-1- beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
Neote K.,et al.Cell 72:415-425(1993).
Gao J.-L.,et al.J. Exp. Med. 177:1421-1427(1993).
Nomura H.,et al.Int. Immunol. 5:1239-1249(1993).
Ko J.,et al.FASEB J. 18:890-892(2004).
Sung H.J.,et al.Exp. Mol. Med. 40:332-338(2008).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.