|Application ||WB, E|
|Calculated MW||54084 Da|
|Other Names||Solute carrier family 2, facilitated glucose transporter member 1, Glucose transporter type 1, erythrocyte/brain, GLUT-1, HepG2 glucose transporter, SLC2A1, GLUT1|
|Target/Specificity||This SLC2A1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 464-497 amino acids from the C-terminal region of human SLC2A1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC2A1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Melanosome. Note=Localizes primarily at the cell surface Identified by mass spectrometry in melanosome fractions from stage I to stage IV|
|Tissue Location||Detected in erythrocytes (at protein level). Expressed at variable levels in many human tissues|
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Provided below are standard protocols that you may find useful for product applications.
Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
Mueckler M.,et al.Science 229:941-945(1985).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Fukumoto H.,et al.Diabetes 37:657-661(1988).
Yu W.,et al.Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases.
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