|Application ||WB, E|
|Calculated MW||87944 Da|
|Other Names||YY1-associated protein 1, Hepatocellular carcinoma susceptibility protein, Hepatocellular carcinoma-associated protein 2, YY1AP1, HCCA2, YY1AP|
|Target/Specificity||This YY1AP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 138-168 amino acids from human YY1AP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||YY1AP1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Enhances transcription activation by YY1. May play a role in cell cycle regulation.|
|Cellular Location||Cytoplasm. Nucleus.|
|Tissue Location||Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.|
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Provided below are standard protocols that you may find useful for product applications.
Enhances transcription activation by YY1. May play a role in cell cycle regulation.
Wang Z.-X.,et al.Br. J. Cancer Suppl. 85:1162-1167(2001).
Wang C.-Y.,et al.J. Biol. Chem. 279:17750-17755(2004).
Zeng J.Z.,et al.Oncogene 21:4932-4943(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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