|Application ||WB, E|
|Calculated MW||36964 Da|
|Other Names||Aflatoxin B1 aldehyde reductase member 4, 1---, AFB1 aldehyde reductase 3, AFB1-AR 3, Aldoketoreductase 7-like, AKR7L, AFAR3, AKR7A4|
|Target/Specificity||This AKR7L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 207-237 amino acids from the Central region of human AKR7L.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AKR7L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).|
|Tissue Location||Mainly expressed in uterus.|
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Provided below are standard protocols that you may find useful for product applications.
Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity).
Gregory S.G.,et al.Nature 441:315-321(2006).
Praml C.,et al.Oncogene 22:4765-4773(2003).
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