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(DANRE) srrt Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - (DANRE) srrt Antibody (C-Term) AP21600b
    All lanes : Anti-srrt Antibody (C-Term) at 1:2000 dilution Lane 1: Zebrafish muscle lysates Lane 2: Zebrafish lysates Lane 3: Jurkat whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 103 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q66I22
Reactivity Human, Zebrafish
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 103274 Da
Additional Information
Gene ID 192311
Other Names Serrate RNA effector molecule homolog, Arsenite-resistance protein 2, srrt, ars2
Target/Specificity This DANRE srrt antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 733-766 amino acids from DANRE srrt.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(DANRE) srrt Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name srrt
Synonyms ars2
Function Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
Cellular Location Nucleus, nucleoplasm. Cytoplasm. Note=Predominantly nuclear. Shuttles between the nucleus and the cytoplasm (By similarity)
Research Areas
Citations (0)

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Background

Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs (By similarity). Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self- renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).

References

Golling G.,et al.Nat. Genet. 31:135-140(2002).
Howe K.,et al.Nature 496:498-503(2013).

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$ 295.00
$ 99.00
Cat# AP21600b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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