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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NAGS Antibody (C-term)   

NAGS Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NAGS Antibody (C-term) AP21612b
    Anti-NAGS Antibody (C-term)at 1:1000 dilution + K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8N159
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 58156 Da
Additional Information
Gene ID 162417
Other Names N-acetylglutamate synthase, mitochondrial, Amino-acid acetyltransferase, N-acetylglutamate synthase long form, N-acetylglutamate synthase short form, N-acetylglutamate synthase conserved domain form, NAGS
Target/Specificity This NAGS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 516-550 amino acids from the C-terminal region of human NAGS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNAGS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NAGS
Function Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity.
Cellular Location Mitochondrion matrix.
Tissue Location Highly expressed in the adult liver, kidney and small intestine. Weakly expressed in the fetal liver, lung, pancreas, placenta, heart and brain tissue
Research Areas
Citations (0)

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Background

Plays a role in the regulation of ureagenesis by producing the essential cofactor N-acetylglutamate (NAG), thus modulating carbamoylphosphate synthase I (CPSI) activity.

References

Haeberle J.,et al.Hum. Mutat. 21:593-597(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Caldovic L.,et al.Biochem. Biophys. Res. Commun. 299:581-586(2002).
Zhao G.,et al.PLoS ONE 8:E70369-E70369(2013).
Schmidt E.,et al.Biochim. Biophys. Acta 1740:54-59(2005).

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$ 295.00
$ 99.00
Cat# AP21612b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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