|Application ||WB, E|
|Calculated MW||25565 Da|
|Other Names||Cytochrome c oxidase subunit 2, Cytochrome c oxidase polypeptide II, MT-CO2, COII, COXII, MTCO2|
|Target/Specificity||This MT-CO2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 169-201 amino acids from the C-terminal region of human MT-CO2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MT-CO2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.|
|Cellular Location||Mitochondrion inner membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.
Anderson S.,et al.Nature 290:457-465(1981).
Power M.D.,et al.Nucleic Acids Res. 17:6734-6734(1989).
Barrell B.G.,et al.Nature 282:189-194(1979).
Horai S.,et al.Proc. Natl. Acad. Sci. U.S.A. 92:532-536(1995).
Ruvolo M.,et al.Mol. Biol. Evol. 10:1115-1135(1993).
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