|Application ||WB, E|
|Calculated MW||21542 Da|
|Other Names||Signal peptidase complex catalytic subunit SEC11C, Microsomal signal peptidase 21 kDa subunit, SPase 21 kDa subunit, SEC11 homolog C, SEC11-like protein 3, SPC21, SEC11C, SEC11L3, SPC21, SPCS4C|
|Target/Specificity||This SEC11C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 85-120 amino acids from the Central region of human SEC11C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SEC11C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||SEC11L3, SPC21, SPCS4C|
|Function||Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.|
|Cellular Location||Microsome membrane; Single- pass type II membrane protein. Endoplasmic reticulum membrane; Single-pass type II membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
Li Y.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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