|Application ||WB, E|
|Calculated MW||45399 Da|
|Other Names||Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4|
|Target/Specificity||This APOA4 antibody is generated from a rabbit immunized with a recombinant protein.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||APOA4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.|
|Tissue Location||Synthesized primarily in the intestine and secreted in plasma|
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Provided below are standard protocols that you may find useful for product applications.
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Karathanasis S.K.,et al.Biochemistry 25:3962-3970(1986).
Karathanasis S.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 83:8457-8461(1986).
Elshourbagy N.A.,et al.J. Biol. Chem. 262:7973-7981(1987).
Yang C.,et al.Biochim. Biophys. Acta 1002:231-237(1989).
Fullerton S.M.,et al.Hum. Genet. 115:36-56(2004).
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