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ATXN2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ATXN2 Antibody (Center) AP21768c
    All lanes : Anti-ATXN2 Antibody (Center) at 1:2000 dilution Lane 1: human skeletal muscle lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 140 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99700
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 140283 Da
Additional Information
Gene ID 6311
Other Names Ataxin-2, Spinocerebellar ataxia type 2 protein, Trinucleotide repeat-containing gene 13 protein, ATXN2, ATX2, SCA2, TNRC13
Target/Specificity This ATXN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 725-757 amino acids from the Central region of human ATXN2.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATXN2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATXN2
Synonyms ATX2, SCA2, TNRC13
Function Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.
Cellular Location Cytoplasm.
Tissue Location Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus
Research Areas
Citations (0)

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Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.


Pulst S.-M.,et al.Nat. Genet. 14:269-276(1996).
Sanpei K.,et al.Nat. Genet. 14:277-284(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
Imbert G.,et al.Nat. Genet. 14:285-291(1996).

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$ 295.00
$ 99.00
Cat# AP21768c
(40 western blots)
Availability: In Stock
Bulk Size
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