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FGF12 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FGF12 Antibody (Center) AP21840c
    All lanes : Anti-FGF12 Antibody (Center) at 1:1000 dilution Lane 1: human brain lysate Lane 2: mouse brain lysate Lane 3: rat brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 27 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P61328
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 27399 Da
Additional Information
Gene ID 2257
Other Names Fibroblast growth factor 12, FGF-12, Fibroblast growth factor homologous factor 1, FHF-1, Myocyte-activating factor, FGF12, FGF12B, FHF1
Target/Specificity This FGF12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 159-191 amino acids from the Central region of human FGF12.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGF12 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF12
Synonyms FGF12B, FHF1
Function Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation.
Cellular Location Nucleus.
Tissue Location Brain, eye and testis; highly expressed in embryonic retina, olfactory epithelium, olfactory bulb, and in a segmental pattern of the body wall; in adult olfactory bulb, less in cerebellum, deep cerebellar nuclei, cortex and multiple midbrain structures
Research Areas
Citations (0)
citation

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Background

Probably involved in nervous system development and function.

References

Smallwood P.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:9850-9857(1996).
Kok L.D.S.,et al.Biochem. Biophys. Res. Commun. 255:717-721(1999).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 182.50
$ 70.00
Cat# AP21840c
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