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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FXC1 Antibody (N-term)   

FXC1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FXC1 Antibody (N-term) AP21868a
    All lanes : Anti-FXC1 Antibody (N-term) at 1:2000 dilution Lane 1: human heart lysate Lane 2: rat liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 12 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y5J6
Other Accession Q3SZW4, Q9WV96, Q5RDJ0, Q9R1B1
Reactivity Human, Rat
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 11586 Da
Additional Information
Gene ID 26515
Other Names Mitochondrial import inner membrane translocase subunit Tim10 B, Fracture callus protein 1, FxC1, Mitochondrial import inner membrane translocase subunit Tim9 B, TIMM10B, Tim10b, TIMM10B, FXC1, TIM9B, TIMM9B
Target/Specificity This FXC1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 15-48 amino acids from the N-terminal region of human FXC1.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFXC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TIMM10B
Synonyms FXC1, TIM9B, TIMM9B
Function Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.
Cellular Location Mitochondrion inner membrane; Peripheral membrane protein
Tissue Location Ubiquitous, with highest expression in heart, kidney, liver and skeletal muscle.
Research Areas
Citations (0)

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Background

Component of the TIM22 complex, a complex that mediates the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane. The TIM22 complex forms a twin- pore translocase that uses the membrane potential as the external driving force. In the TIM22 complex, it may act as a docking point for the soluble 70 kDa complex that guides the target proteins in transit through the aqueous mitochondrial intermembrane space.

References

Jin H.,et al.Genomics 61:259-267(1999).
Bauer M.F.,et al.FEBS Lett. 464:41-47(1999).
Peng Y.,et al.Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
Rothbauer U.,et al.J. Biol. Chem. 276:37327-37334(2001).
Muehlenbein N.,et al.J. Biol. Chem. 279:13540-13546(2004).

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$ 99.00
Cat# AP21868a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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