|Application ||WB, E|
|Calculated MW||112601 Da|
|Other Names||StAR-related lipid transfer protein 8, Deleted in liver cancer 3 protein, DLC-3, START domain-containing protein 8, StARD8, START-GAP3, STARD8, DLC3, KIAA0189|
|Target/Specificity||This STARD8 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 220-255 amino acids from human STARD8.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STARD8 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1.|
|Cellular Location||Cell junction, focal adhesion|
|Tissue Location||Widely expressed with highest levels in kidney, lung and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5- bisphosphate by PLCD1.
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ross M.T.,et al.Nature 434:325-337(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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