|Application ||WB, IHC-P, E|
|Other Accession||Q28024, Q9DAS9, Q5RBQ0|
|Calculated MW||8006 Da|
|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12, GNG12|
|Target/Specificity||This GNG12 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 37-68 amino acids from human GNG12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNG12 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.
Hurowitz E.H.,et al.DNA Res. 7:111-120(2000).
Yang L.,et al.Submitted (JAN-1999) to the EMBL/GenBank/DDBJ databases.
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Cook L.A.,et al.Protein Sci. 10:2548-2555(2001).
Puhl H.L. III,et al.Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
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