|Application ||WB, E|
|Calculated MW||35813 Da|
|Other Names||SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related, SMARCE1-related protein, BRCA2-associated factor 35, HMG box-containing protein 20B, HMG domain-containing protein 2, HMG domain-containing protein HMGX2, Sox-like transcriptional factor, Structural DNA-binding protein BRAF35, HMG20B, BRAF35, HMGX2, HMGXB2, SMARCE1R|
|Target/Specificity||This HMG20B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-43 amino acids from human HMG20B.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HMG20B Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BRAF35, HMGX2, HMGXB2, SMARCE1R|
|Function||Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.|
|Cellular Location||Nucleus. Chromosome. Note=Localized to condensed chromosomes in mitosis in conjunction with BRCA2|
|Tissue Location||Ubiquitously expressed in adult tissues.|
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Provided below are standard protocols that you may find useful for product applications.
Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters.
Sumoy L.,et al.Cytogenet. Cell Genet. 88:62-67(2000).
Marmorstein L.Y.,et al.Cell 104:247-257(2001).
Lee Y.M.,et al.Biochim. Biophys. Acta 1574:269-276(2002).
Wang C.,et al.Biochem. Biophys. Res. Commun. 295:129-135(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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