|Application ||WB, E|
|Calculated MW||268571 Da|
|Other Names||Neuroblastoma-amplified sequence, Neuroblastoma-amplified gene protein, NBAS, NAG|
|Target/Specificity||This NBAS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 628-661 amino acids from the human NBAS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NBAS Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in Golgi-to-endoplasmic reticulum (ER) retrograde tranport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418).|
|Cellular Location||Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein|
|Tissue Location||Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblastoma cell lines|
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Provided below are standard protocols that you may find useful for product applications.
Scott D.K.,et al.Gene 307:1-11(2003).
Hillier L.W.,et al.Nature 434:724-731(2005).
Wimmer K.,et al.Oncogene 18:233-238(1999).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Fruehwald M.C.,et al.J. Med. Genet. 37:501-509(2000).
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