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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   EFS Antibody (Center)   

EFS Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - EFS Antibody (Center) AP21926c
    All lanes : Anti-EFS Antibody (Center) at 1:1000-1:2000 dilution Lane 1: human fetal liver lysate Lane 2: human lung lysate Lane 3: Jurkat whole cell lysate Lane 4: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 59 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43281
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 58815 Da
Additional Information
Gene ID 10278
Other Names Embryonal Fyn-associated substrate, hEFS, Cas scaffolding protein family member 3, EFS, CASS3
Target/Specificity This EFS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 367-399 amino acids from the Central region of human EFS.
Dilution WB~~1:1000-1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsEFS Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EFS
Synonyms CASS3
Function Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity).
Tissue Location The protein has been detected in lung and placenta
Research Areas
Citations (0)

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Background

Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES (By similarity).

References

Ishino M.,et al.Oncogene 15:1741-1745(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Sjoeblom T.,et al.Science 314:268-274(2006).

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$ 295.00
$ 99.00
Cat# AP21926c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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