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USP32 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8NFA0 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 181656 Da |
| Gene ID | 84669 |
|---|---|
| Other Names | Ubiquitin carboxyl-terminal hydrolase 32, 3.4.19.12, Deubiquitinating enzyme 32, Renal carcinoma antigen NY-REN-60, Ubiquitin thioesterase 32, Ubiquitin-specific-processing protease 32, USP32, USP10 |
| Target/Specificity | This USP32 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 438-470 amino acids from human USP32. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | USP32 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | USP32 |
|---|---|
| Synonyms | USP10 |
| Function | Deubiquitinase that can remove conjugated ubiquitin from target proteins, such as RAB7A and LAMTOR1 (PubMed:36476874). Acts as a positive regulator of the mTORC1 signaling by mediating deubiquitination of LAMTOR1, thereby promoting the association between LAMTOR1 and the lysosomal V-ATPase complex and subsequent activation of the mTORC1 complex (PubMed:36476874). |
| Cellular Location | Golgi apparatus membrane; Lipid-anchor |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
References
Paulding C.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 100:2507-2511(2003).
Sha J.H.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Zody M.C.,et al.Nature 440:1045-1049(2006).
Scanlan M.J.,et al.Int. J. Cancer 83:456-464(1999).
Olsen J.V.,et al.Cell 127:635-648(2006).
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