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CIDEB Antibody (C-erm)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CIDEB Antibody (C-erm) AP21953a
    Anti-CIDEB Antibody (C-erm) at 1:2000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9UHD4
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Additional Information
Other Names Cell death activator CIDE-B, Cell death-inducing DFFA-like effector B, CIDEB
Target/Specificity This CIDEB antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-183 amino acids from human CIDEB.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCIDEB Antibody (C-erm) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CIDEB
Function Activates apoptosis.
Tissue Location Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen EMBL; AF190901; AAF23324.1; -; mRNA EMBL; AF218586; AAF27658.1; -; mRNA EMBL; AF544398; AAN37907.1; -; mRNA EMBL; AK000387; BAA91132.1; -; mRNA EMBL; CH471078; EAW66031.1; -; Genomic_DNA EMBL; CH471078; EAW66032.1; -; Genomic_DNA EMBL; CH471078; EAW66033.1; -; Genomic_DNA EMBL; BC035970; AAH35970.1; -; mRNA CCDS; CCDS32056.1; - RefSeq; NP_001305736.1; NM_001318807.1 RefSeq; NP_055245.2; NM_014430.2 RefSeq; XP_011534961.1; XM_011536659.2 RefSeq; XP_016876710.1; XM_017021221.1 UniGene; Hs.642693; - UniGene; Hs.708040; - PDB; 1D4B; NMR; -; A=1-116 PDBsum; 1D4B; - ProteinModelPortal; Q9UHD4; - SMR; Q9UHD4; - BioGrid; 118027; 9 IntAct; Q9UHD4; 62 STRING; 9606.ENSP00000258807; - iPTMnet; Q9UHD4; - PhosphoSitePlus; Q9UHD4; - BioMuta; CIDEB; - DMDM; 20141283; - EPD; Q9UHD4; - PaxDb; Q9UHD4; - PeptideAtlas; Q9UHD4; - PRIDE; Q9UHD4; - ProteomicsDB; 84324; - DNASU; 27141; - Ensembl; ENST00000258807; ENSP00000258807; ENSG00000136305 Ensembl; ENST00000336557; ENSP00000337731; ENSG00000136305 Ensembl; ENST00000554411; ENSP00000451089; ENSG00000136305 Ensembl; ENST00000642223; ENSP00000493738; ENSG00000285199 Ensembl; ENST00000644519; ENSP00000494868; ENSG00000285199 Ensembl; ENST00000644672; ENSP00000495235; ENSG00000285199 GeneID; 27141; - KEGG; hsa:27141; - UCSC; uc001won.4; human CTD; 27141; - DisGeNET; 27141; - EuPathDB; HostDB:ENSG00000136305.11; - GeneCards; CIDEB; - HGNC; HGNC:1977; CIDEB HPA; HPA001272; - MIM; 604441; gene neXtProt; NX_Q9UHD4; - OpenTargets; ENSG00000136305; - PharmGKB; PA26515; - eggNOG; ENOG410IIBQ; Eukaryota eggNOG; ENOG4111N1Y; LUCA GeneTree; ENSGT00390000018596; - HOGENOM; HOG000029211; - HOVERGEN; HBG050961; - InParanoid; Q9UHD4; - OMA; VWTSAPP; - OrthoDB; EOG091G0KVY; - PhylomeDB; Q9UHD4; - TreeFam; TF334321; - SignaLink; Q9UHD4; - ChiTaRS; CIDEB; human EvolutionaryTrace; Q9UHD4; - GenomeRNAi; 27141; - PRO; PR:Q9UHD4; - Proteomes; UP000005640; Chromosome 14 Bgee; ENSG00000136305; - CleanEx; HS_CIDEB; - ExpressionAtlas; Q9UHD4; baseline and differential Genevisible; Q9UHD4; HS GO; GO:0005829; C:cytosol; IDA:MGI GO; GO:0005811; C:lipid droplet; IBA:GO_Central GO; GO:0048471; C:perinuclear region of cytoplasm; IDA:AgBase GO; GO:0042802; F:identical protein binding; IPI:IntAct GO; GO:0097202; P:activation of cysteine-type endopeptidase activity; IDA:AgBase GO; GO:0006915; P:apoptotic process; IDA:MGI GO; GO:0097194; P:execution phase of apoptosis; ISS:BHF-UCL GO; GO:0008630; P:intrinsic apoptotic signaling pathway in response to DNA damage; TAS:ProtInc GO; GO:0010942; P:positive regulation of cell death; IDA:AgBase GO; GO:0090200; P:positive regulation of release of cytochrome c from mitochondria; IDA:AgBase InterPro; IPR003508; CIDE-N_dom Pfam; PF02017; CIDE-N; 1 SMART; SM00266; CAD; 1 PROSITE; PS51135; CIDE_N; 1 1: Evidence at protein level; 3D-structure; Apoptosis; Complete proteome; Reference proteome CHAIN 1 219 Cell death activator CIDE-B /FTId=PRO_0000144720 DOMAIN 34 110 CIDE-N. {ECO:0000255|PROSITE- ProRule:PRU00447} CONFLICT 120 120 L -> P (in Ref. 1; AAF23324) CONFLICT 124 124 R -> S (in Ref. 1; AAF23324) CONFLICT 132 132 A -> G (in Ref. 1; AAF23324) STRAND 9 12 {ECO:0000244|PDB:1D4B} STRAND 36 41 {ECO:0000244|PDB:1D4B} STRAND 43 46 {ECO:0000244|PDB:1D4B} STRAND 48 53 {ECO:0000244|PDB:1D4B} HELIX 59 67 {ECO:0000244|PDB:1D4B} STRAND 74 77 {ECO:0000244|PDB:1D4B} TURN 78 81 {ECO:0000244|PDB:1D4B} STRAND 82 84 {ECO:0000244|PDB:1D4B} HELIX 88 92 {ECO:0000244|PDB:1D4B} STRAND 93 95 {ECO:0000244|PDB:1D4B} SEQUENCE 219 AA; 24678 MW; E0B4E5EF1F7C912D CRC64; MEYLSALNPS DLLRSVSNIS SEFGRRVWTS APPPQRPFRV CDHKRTIRKG LTAATRQELL AKALETLLLN GVLTLVLEED GTAVDSEDFF QLLEDDTCLM VLQSGQSWSP TRSGVLSYGL GRERPKHSKD IARFTFDVYK QNPRDLFGSL NVKATFYGLY SMSCDFQGLG PKKVLRELLR WTSTLLQGLG HMLLGISSTL RHAVEGAEQW QQKGRLHSY
Research Areas
Citations (0)

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Background

Activates apoptosis.

References

Lugovskoy A.A.,et al.Cell 99:747-755(1999).
Inohara N.,et al.EMBO J. 17:2526-2533(1998).
Liang L.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
$ 99.00
Cat# AP21953a
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Quantity:
(40 western blots)
Availability: In Stock
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