|Application ||WB, E|
|Calculated MW||12911 Da|
|Other Names||Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, Ghrelin-27, Ghrelin-28, Ghrelin, Obestatin, GHRL, MTLRP|
|Target/Specificity||This GHRL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-43 amino acids from human GHRL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GHRL Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.|
|Tissue Location||Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy|
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Provided below are standard protocols that you may find useful for product applications.
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Kojima M.,et al.Nature 402:656-660(1999).
Tomasetto C.,et al.Gastroenterology 119:395-405(2000).
Wajnrajch M.P.,et al.J. Endocr. Genet. 1:231-233(2000).
Hosoda H.,et al.J. Biol. Chem. 278:64-70(2003).
Seim I.,et al.BMC Genomics 8:298-298(2007).
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