|Application ||WB, E|
|Calculated MW||12911 Da|
|Other Names||Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, Ghrelin-27, Ghrelin-28, Ghrelin, Obestatin, GHRL, MTLRP|
|Target/Specificity||This GHRL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-43 amino acids from human GHRL.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GHRL Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.|
|Tissue Location||Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Kojima M.,et al.Nature 402:656-660(1999).
Tomasetto C.,et al.Gastroenterology 119:395-405(2000).
Wajnrajch M.P.,et al.J. Endocr. Genet. 1:231-233(2000).
Hosoda H.,et al.J. Biol. Chem. 278:64-70(2003).
Seim I.,et al.BMC Genomics 8:298-298(2007).
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