|Application ||WB, E|
|Calculated MW||38045 Da|
|Other Names||CMP-N-acetylneuraminate-beta-galactosamide-alpha-2, 3-sialyltransferase 4, Alpha 2, 3-ST 4, Beta-galactoside alpha-2, 3-sialyltransferase 4, 2.4.99.-, Alpha 2, 3-sialyltransferase IV, Gal-NAc6S, Gal-beta-1, 4-GalNAc-alpha-2, 3-sialyltransferase, SAT-3, ST-4, ST3Gal IV, ST3GalIV, ST3GalA.2, STZ, Sialyltransferase 4C, SIAT4-C, ST3GAL4, CGS23, NANTA3, SIAT4C, STZ|
|Target/Specificity||This ST3GAL4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 26-57 amino acids from human ST3GAL4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ST3GAL4 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CGS23, NANTA3, SIAT4C, STZ|
|Function||Catalyzes the formation of the NeuAc-alpha-2,3-Gal-beta- 1,4-GlcNAc-, and NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Note=Membrane- bound form in trans cisternae of Golgi. Secreted into the body fluid|
|Tissue Location||Highly expressed in adult placenta, ovary and testes|
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Provided below are standard protocols that you may find useful for product applications.
It may catalyze the formation of the NeuAc-alpha-2,3- Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc- sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. Also acts on the corresponding 1,3- galactosyl derivative.
Kitagawa H.,et al.J. Biol. Chem. 271:931-938(1996).
Kitagawa H.,et al.J. Biol. Chem. 269:1394-1401(1994).
Sasaki K.,et al.J. Biol. Chem. 268:22782-22787(1993).
Grahn A.,et al.Glycoconj. J. 18:759-767(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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