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>   home   >   Products   >   Primary Antibodies   >   HEXIM2 Antibody (C-Term)   

HEXIM2 Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - HEXIM2 Antibody (C-Term) AP22031b
    All lanes : Anti-HEXIM2 Antibody (C-Term) at 1:8000 dilution Lane 1: mouse testis lysate Lane 2: U-2OS whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 32 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q96MH2
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 32419 Da
Additional Information
Gene ID 124790
Other Names Protein HEXIM2, Hexamethylene bis-acetamide-inducible protein 2, HEXIM2
Target/Specificity This HEXIM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 235-269 amino acids from of human HEXIM2.
Dilution WB~~1:8000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHEXIM2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HEXIM2
Function Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Cellular Location Nucleus.
Tissue Location Ubiquitously expressed with higher expression in testis. HEXIM1 and HEXIM2 are differentially expressed
Citations (0)

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Background

Transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor. In cooperation with 7SK snRNA sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.

References

Petroziello J.,et al.Oncogene 23:7734-7745(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Byers S.A.,et al.J. Biol. Chem. 280:16360-16367(2005).
Yik J.H.N.,et al.J. Biol. Chem. 280:16368-16376(2005).

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$ 295.00
$ 99.00
Cat# AP22031b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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