|Application ||WB, E|
|Calculated MW||284525 Da|
|Other Names||Probable JmjC domain-containing histone demethylation protein 2C, 1.14.11.-, Jumonji domain-containing protein 1C, Thyroid receptor-interacting protein 8, TR-interacting protein 8, TRIP-8, JMJD1C, JHDM2C, KIAA1380, TRIP8|
|Target/Specificity||This JMJD1C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2019-2051 amino acids from human JMJD1C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||JMJD1C Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||JHDM2C, KIAA1380, TRIP8|
|Function||Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).|
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Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity).
Wolf S.S.,et al.Arch. Biochem. Biophys. 460:56-66(2007).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Deloukas P.,et al.Nature 429:375-381(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Nagase T.,et al.DNA Res. 7:65-73(2000).
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