Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
C8orf80 Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q68CJ6 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 91132 Da |
| Gene ID | 389643 |
|---|---|
| Other Names | Nuclear GTPase SLIP-GC, 3.6.1.-, Speckled-like pattern in the germinal center, NUGGC, C8orf80 |
| Target/Specificity | This C8orf80 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-59 amino acids from human C8orf80. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | C8orf80 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NUGGC |
|---|---|
| Synonyms | C8orf80 |
| Function | Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA (PubMed:19734146). Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity). |
| Cellular Location | Nucleus speckle. |
| Tissue Location | Expressed in germinal center B-cell and in lymphomas derived from germinal center B-cell |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role as replication-related GTPase protein in germinal center B-cell.
References
Nusbaum C.,et al.Nature 439:331-335(2006).
Yamada S.,et al.Oncogene 23:5901-5911(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Richter K.,et al.J. Biol. Chem. 284:30652-30661(2009).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
