|Application ||WB, E|
|Calculated MW||11840 Da|
|Other Names||Alpha-hemoglobin-stabilizing protein, Erythroid differentiation-related factor, Erythroid-associated factor, AHSP, EDRF, ERAF|
|Target/Specificity||This AHSP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 39-73 amino acids from the Central region of human AHSP.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AHSP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.|
|Tissue Location||Expressed in blood and bone marrow.|
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Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
Miele G.,et al.Nat. Med. 7:361-364(2001).
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).
Michel U.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Finning K.,et al.Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
Kihm A.J.,et al.Nature 417:758-763(2002).
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