AHSP Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9NZD4 |
Reactivity | Human |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 11840 Da |
Gene ID | 51327 |
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Other Names | Alpha-hemoglobin-stabilizing protein, Erythroid differentiation-related factor, Erythroid-associated factor, AHSP, EDRF, ERAF |
Target/Specificity | This AHSP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 39-73 amino acids from the Central region of human AHSP. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | AHSP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AHSP |
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Synonyms | EDRF, ERAF |
Function | Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta- thalassemia. |
Cellular Location | Cytoplasm. |
Tissue Location | Expressed in blood and bone marrow. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.
References
Miele G.,et al.Nat. Med. 7:361-364(2001).
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).
Michel U.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Finning K.,et al.Submitted (FEB-2002) to the EMBL/GenBank/DDBJ databases.
Kihm A.J.,et al.Nature 417:758-763(2002).
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