|Application ||WB, E|
|Calculated MW||59941 Da|
|Other Names||UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, 220.127.116.11, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, UDP-glucuronosyltransferase 1A9, lugP4, UGT1A9, GNT1, UGT1|
|Target/Specificity||This UGT1A9 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 62-92 amino acids from human UGT1A9.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UGT1A9 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.|
|Cellular Location||Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Liver. Isoform 1 and isoform 2 are expressed in liver, kidney, colon, esophagus and small intestine|
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Provided below are standard protocols that you may find useful for product applications.
UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1.
Wooster R.,et al.Biochem. J. 278:465-469(1991).
Ciotti M.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Gong Q.H.,et al.Pharmacogenetics 11:357-368(2001).
Hillier L.W.,et al.Nature 434:724-731(2005).
Owens I.S.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
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