|Application ||WB, E|
|Calculated MW||40519 Da|
|Other Names||Alpha-N-acetylneuraminide alpha-2, 8-sialyltransferase, 188.8.131.52, Alpha-2, 8-sialyltransferase 8A, Ganglioside GD3 synthase, Ganglioside GT3 synthase, Sialyltransferase 8A, SIAT8-A, Sialyltransferase St8Sia I, ST8SiaI, ST8SIA1, SIAT8, SIAT8A|
|Target/Specificity||This ST8SIA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 53-84 amino acids from human ST8SIA1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ST8SIA1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid.|
|Cellular Location||Golgi apparatus membrane; Single-pass type II membrane protein|
|Tissue Location||Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung.|
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Provided below are standard protocols that you may find useful for product applications.
Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid.
Sasaki K.,et al.J. Biol. Chem. 269:15950-15956(1994).
Nara K.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:7952-7956(1994).
Haraguchi M.,et al.Proc. Natl. Acad. Sci. U.S.A. 91:10455-10459(1994).
Nakayama J.,et al.J. Biol. Chem. 271:3684-3691(1996).
Rimoldi S.,et al.Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
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