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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ZMPSTE24 Antibody (C-term)   

ZMPSTE24 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZMPSTE24 Antibody (C-term) AP2415b
    The anti-ZMPSTE24 Pab (Cat. #AP2415b) is used in Western blot to detect ZMPSTE24 in T-47D cell lysate.
  • IHC-P - ZMPSTE24 Antibody (C-term) AP2415b
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75844
Other Accession Q80W54, NP_005848
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54813 Da
Antigen Region 440-470 aa
Additional Information
Gene ID 10269
Other Names CAAX prenyl protease 1 homolog, Farnesylated proteins-converting enzyme 1, FACE-1, Prenyl protein-specific endoprotease 1, Zinc metalloproteinase Ste24 homolog, ZMPSTE24, FACE1, STE24
Target/Specificity This ZMPSTE24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-470 amino acids from the C-terminal region of human ZMPSTE24.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZMPSTE24 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms FACE1, STE24
Function Proteolytically removes the C-terminal three residues of farnesylated proteins. Acts on lamin A/C.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Nucleus inner membrane; Multi-pass membrane protein
Tissue Location Widely expressed. High levels in kidney, prostate, testis and ovary
Research Areas
Citations ( 0 )


ZMPSTE24 is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.


Freije, J.M., et al., Genomics 58(3):270-280 (1999).
Kumagai, H., et al., Biochim. Biophys. Acta 1426(3):468-474 (1999).
Tam, A., et al., J. Cell Biol. 142(3):635-649 (1998).

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$ 295.00
$ 99.00
Cat# AP2415b
(40 western blots)
Availability: In Stock
Bulk Size
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