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> home > Products > Primary Antibodies > Antibody Collections > Mitochondrion > Prohibitin (PHB1) Antibody (N-term)
Prohibitin (PHB1) Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
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- BACKGROUND
Application 
| IHC-P, WB, FC, E |
|---|---|
| Primary Accession | P35232 |
| Other Accession | P84173, Q3T165 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Chicken |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 29804 Da |
| Antigen Region | 92-121 aa |
| Gene ID | 5245 |
|---|---|
| Other Names | Prohibitin, PHB |
| Target/Specificity | This Prohibitin (PHB1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the N-terminal region of human Prohibitin (PHB1). |
| Dilution | WB~~1:2000 IHC-P~~1:100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Prohibitin (PHB1) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PHB1 {ECO:0000303|PubMed:28017329, ECO:0000312|HGNC:HGNC:8912} |
|---|---|
| Function | Protein with pleiotropic attributes mediated in a cell- compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus (PubMed:11302691, PubMed:20959514, PubMed:28017329, PubMed:31522117). Plays a role in adipose tissue and glucose homeostasis in a sex-specific manner (By similarity). Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells (By similarity). |
| Cellular Location | Mitochondrion inner membrane. Nucleus. Cytoplasm. Cell membrane |
| Tissue Location | Widely expressed in different tissues. |
Research Areas
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$ 385.00
Cat# AP2710a
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