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PHB1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PHB1 Antibody (C-term) AP2710b
    Western blot analysis of PHB1 (arrow) using rabbit polyclonal PHB1 Antibody (Human C-term) (Cat.#AP2710b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PHB1 gene (Lane 2) (Origene Technologies).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35232
Other Accession P67779, P67778, Q3T165
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 29804 Da
Antigen Region 182-211 aa
Additional Information
Gene ID 5245
Other Names Prohibitin, PHB
Target/Specificity This PHB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 182-211 amino acids from the C-terminal region of human PHB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPHB1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHB
Function Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.
Cellular Location Mitochondrion inner membrane.
Tissue Location Widely expressed in different tissues.
Research Areas
Citations (0)

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Prohibitin is an evolutionarily conserved protein that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region.


Gregory-Bass,R.C., Int. J. Cancer 122 (9), 1923-1930 (2008)
Ross,J.A., J. Biol. Chem. 283 (8), 4699-4713 (2008)
White,J.J., Genomics 11 (1), 228-230 (1991)

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$ 295.00
$ 99.00
Cat# AP2710b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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