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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   Semaphorin 5A Antibody   

Semaphorin 5A Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Semaphorin 5A Antibody AP2712c
    Western blot analysis of Semaphorin 5A-S106 Antibody(Cat. #AP2712c) in mouse brain tissue lysates (35ug/lane). Semaphorin 5A (arrow) was detected using the purified Pab.
  • WB - Semaphorin 5A Antibody AP2712c
    Semaphorin 5A-S106 Antibody (Cat. #AP2712c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Semaphorin 5A antibody detected the Semaphorin 5A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13591
Other Accession D3ZTD8, Q62217
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 120615 Da
Antigen Region 90-113 aa
Additional Information
Gene ID 9037
Other Names Semaphorin-5A, Semaphorin-F, Sema F, SEMA5A, SEMAF
Target/Specificity This Semaphorin 5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-113 amino acids from human Semaphorin 5A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSemaphorin 5A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SEMAF
Function Bifunctional axonal guidance cue regulated by sulfated proteoglycans; attractive effects result from interactions with heparan sulfate proteoglycans (HSPGs), while the inhibitory effects depend on interactions with chondroitin sulfate proteoglycans (CSPGs) (By similarity). Ligand for receptor PLXNB3. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. May promote angiogenesis by increasing endothelial cell proliferation and migration and inhibiting apoptosis.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Semaphorin 5A belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development.


Weiss,L.A.,, Nature 461 (7265), 802-808 (2009).

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$ 295.00
$ 99.00
Cat# AP2712c
(40 western blots)
Availability: In Stock
Bulk Size
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