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Olfm1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - Olfm1 Antibody (C-term) AP2719b
    Western blot analysis of Noelin-1(Olfm1) (arrow) using rabbit polyclonal Noelin-1(Olfm1) Antibody (C-term) (Cat.#AP2719b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Noelin-1(Olfm1) gene (Lane 2) (Origene Technologies).
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99784
Other Accession Q62609, O88998, Q9IAK4
Reactivity Human
Predicted Chicken, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55343 Da
Antigen Region 434-463 aa
Additional Information
Gene ID 10439
Other Names Noelin, Neuronal olfactomedin-related ER localized protein, Olfactomedin-1, OLFM1, NOE1, NOEL1
Target/Specificity This Olfm1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-463 amino acids from the C-terminal region of human Olfm1.
Dilution WB~~1:1000
Format Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOlfm1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OLFM1
Synonyms NOE1, NOEL1
Function Contributes to the regulation of axonal growth in the embryonic and adult central nervous system by inhibiting interactions between RTN4R and LINGO1. Inhibits RTN4R-mediated axon growth cone collapse (By similarity). May play an important role in regulating the production of neural crest cells by the neural tube (By similarity). May be required for normal responses to olfactory stimuli (By similarity).
Cellular Location Secreted {ECO:0000250|UniProtKB:O88998}. Cell junction, synapse {ECO:0000250|UniProtKB:O88998}. Endoplasmic reticulum {ECO:0000250|UniProtKB:O88998}. Cell projection, axon {ECO:0000250|UniProtKB:O88998}. Perikaryon {ECO:0000250|UniProtKB:O88998}
Research Areas
Citations (0)

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Background

Olfm1 shares extensive sequence similarity with the rat neuronal olfactomedin-related ER localized protein. While the exact function of this protein is not known, its abundant expression in brain suggests that it may have an essential role in nerve tissue.

References

Yokoyama M.,DNA Res. 3:311-320(1996).
Yu W., Genome Res. 7:353-358(1997).
Liu T.,J. Proteome Res. 4:2070-2080(2005).

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Cat# AP2719b
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(40 western blots)
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