|Application ||WB, E|
|Calculated MW||57399 Da|
|Antigen Region||175-205 aa|
|Other Names||Amidophosphoribosyltransferase, ATase, Glutamine phosphoribosylpyrophosphate amidotransferase, GPAT, PPAT, GPAT|
|Target/Specificity||This PPAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-205 amino acids from the Central region of human PPAT.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPAT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Ubiquitously expressed.|
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Provided below are standard protocols that you may find useful for product applications.
PPAT is a member of the purine/pyrimidine phosphoribosyltransferase family. This protein is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosynthesis.
Bera,A.K., J. Biol. Chem. 274 (51), 36498-36504 (1999)
Stanley,W., Cytogenet. Cell Genet. 22 (1-6), 228-231 (1978)
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