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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   DLG7 Antibody (Center)   

DLG7 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DLG7 Antibody (Center) AP2810C
    Western blot analysis of DLG7 Antibody (Center) (Cat. #AP2810c) in 293 cell line lysates (35ug/lane).DLG7 (arrow) was detected using the purified Pab.
  • IHC-P - DLG7 Antibody (Center) AP2810C
    DLG7 Antibody (Center) (Cat. #AP2810c) IHC analysis in formalin fixed and paraffin embedded hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DLG7 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - DLG7 Antibody (Center) AP2810C
    DLG7 Antibody (Center) (Cat. #AP2810c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15398
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 95115 Da
Antigen Region 228-258 aa
Additional Information
Gene ID 9787
Other Names Disks large-associated protein 5, DAP-5, Discs large homolog 7, Disks large-associated protein DLG7, Hepatoma up-regulated protein, HURP, DLGAP5, DLG7, KIAA0008
Target/Specificity This DLG7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-258 amino acids from the Central region of human DLG7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDLG7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DLG7, KIAA0008
Function Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Cellular Location Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=Localizes to the spindle in mitotic cells Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells
Tissue Location Abundantly expressed in fetal liver. Expressed at lower levels in bone marrow, testis, colon, and placenta
Research Areas
Citations (0)

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DLG7 is potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. DLG7 is mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. DLG7 is key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.


de Reynies, A., et al. J. Clin. Oncol. 27(7):1108-1115(2009) Wong, J., et al. Mol. Biol. Cell 19(5):2083-2091(2008) Gudmundsson, K.O., et al. Stem Cells 25(6):1498-1506(2007)

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Cat# AP2810C
(40 western blots)
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