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ACTR3 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP2891b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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ACTR3 Antibody (C-term) - Product info | |
| Application | WB, IHC, FC
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| Primary Accession | P61158 |
| Other Accession | Q4V7C7, Q99JY9, Q90WD0, P61157 |
| Reactivity | Human |
| Predicted | Bovine, Chicken, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 47371 Da |
ACTR3 Antibody (C-term) - Additional info | |
| Gene ID 10096 | |
| Other Names ACTR3; ARP3; Actin-related protein 3; Actin-like protein 3 | |
| Target/Specificity This ACTR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387~416 amino acids from the C-terminal region of human ACTR3. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACTR3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACTR3 Antibody (C-term) - Protein Information | |
| Name ACTR3 | |
| Synonyms ARP3 | |
| Function Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis | |
| Cellular Location Cytoplasm, cytoskeleton. Cell projection. | |
ACTR3 Antibody (C-term) - Related products
AP2891b: ACTR3 Antibody (C-term)
AP2891c: ACTR3 Antibody (Center)
RI10093: ACTR3 predesign siRNA
BP2891b: ACTR3 Antibody (C-term) Blocking Peptide
ACTR3 Antibody (C-term) - Application data
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Western blot analysis of ACTR3 Antibody (C-term) (Cat. #AP2891b) in A2058 cell line lysates (35ug/lane). ACTR3 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ACTR3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Flow cytometric analysis of hela cells using ACTR3 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ACTR3 Antibody (C-term) - Research Areas
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BACKGROUND
ACTR3 is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.
REFERENCES
Weisswange,I., et. al., Nature 458 (7234), 87-91 (2009)
