|Application ||WB, E|
|Calculated MW||66194 Da|
|Antigen Region||548-577 aa|
|Other Names||WD repeat-containing protein 1, Actin-interacting protein 1, AIP1, NORI-1, WDR1|
|Target/Specificity||This WDR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-577 amino acids from the C-terminal region of human WDR1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||WDR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection, podosome|
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Provided below are standard protocols that you may find useful for product applications.
WDR1 is a protein containing 9 WD repeats. WD repeats are approximately 30- to 40-amino acid domains containing several conserved residues, mostly including a trp-asp at the C-terminal end. WD domains are involved in protein-protein interactions. This protein may help induce the disassembly of actin filaments.
McArdle,P.F., et.al., Arthritis Rheum. 58 (9), 2874-2881 (2008)
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