|Application ||WB, IHC-P, FC, E|
|Other Accession||O35244, Q9TSX9, O08709, Q2PFL9, Q5ZJF4, O77834|
|Predicted||Bovine, Chicken, Monkey, Mouse, Pig, Rat|
|Calculated MW||25035 Da|
|Antigen Region||197-224 aa|
|Other Names||Peroxiredoxin-6, 1-Cys peroxiredoxin, 1-Cys PRX, 24 kDa protein, Acidic calcium-independent phospholipase A2, aiPLA2, 311-, Antioxidant protein 2, Liver 2D page spot 40, Non-selenium glutathione peroxidase, NSGPx, Red blood cells page spot 12, PRDX6, AOP2, KIAA0106|
|Target/Specificity||This PRDX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-224 amino acids from the C-terminal region of human PRDX6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRDX6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.|
|Cellular Location||Cytoplasm. Lysosome. Cytoplasmic vesicle. Note=Also found in lung secretory organelles.|
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Provided below are standard protocols that you may find useful for product applications.
PRDX6is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.
Sorokina,E.M., et.al., Am. J. Physiol. Lung Cell Mol. Physiol. 297 (5), L871-L880 (2009)
Manevich,Y., et.al., Arch. Biochem. Biophys. 485 (2), 139-149 (2009)
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